Sympathetic ophthalmia

Rare autoimmune inflammatory disorder usu. occur following a penetrating injury (trauma/ surgery) of one eye.

Pathophysiology: eye tisssue enter blood circulation (during the penetrating injury) causing sensitization of body immune system and produce antibodies towards eye tissue.

symptoms:

-floating spots

-reduce sensation

-increase sensitivity to light

-pain in both eyes

sign:

-severe reaction in anterior chamber

-with large greasy appearing deposits in cornea (mutton fat keratic precipitates)

-Dalen Fuch's nodule in choroid

-thickening of uveal tract

may acompany: pailloedema, cataract, glaucoma, vitiligo, poliosis (patches of white eyelash)

DALEN FUCH'S NODULE

Fundus photo of sympathetic ophthalmia with an exudative retinal detachmen